K.K. DNAFORM


Yoshihide Hayashizaki  

Representative CEO, K.K. DNAFORM, Representative CEO, K.K. Mirai Genomics,  
Chairman & CEO, K.K. SS Dnaform
2-6-29 Tsurumi-chuo, Tsurumi-ku, Yokohama, Kanagawa, 230-0051, Japan
Phone: +81- 45-510-0607
Fax: +81- 45-510-0608
e-mail:yoshihide.hayashizaki@dnaform.jp

EDUCATION

1982M.D.Medical faculty of Osaka University, Japan
1986Ph.D.Osaka University, Institute for Molecular and Cellular Biology, Japan

MAJOR EMPLOYMENT

1995-1998Project Director, RIKEN genome exploration research project, Japan
1995-2008Chief Scientist, Department Director and Chairman, Genome Science Laboratory, RIKEN, Japan
1998-2008Project Director, RIKEN Genome Exploration Research Group, Genomic Sciences Center, Japan
2008-2013Director, Omics Science Center, RIKEN Yokohama Institute, Japan
2013-2021Program Director, RIKEN Preventive Medicine and Diagnosis Innovation Program, Japan
2015-2018Advisor to President, RIKEN
2016-2021Core Principal Investigator, RIKEN
2021-presentRepresentative CEO, K.K. Mirai Genomics, K.K. DNAFORM, Chairman & CEO, K.K. SS Dnaform

POSITIONS

1995-2010Professor, Tsukuba University Medical School
1998-2013Professor, Graduate school of Integrated Science, Yokohama City University, Japan
2003-2009Guest Professor, University of Queendland, Australia
2003-2011Guest Professor, Karolinska Institute, Sweden
2011-presentScientific Advisory Board Member, Science for Life Laboratory (SciLifeLab), Sweden
2012-2013Visiting Scholar, Beijing Genomics Institute (BGI), China
2012-2015Board of Trustees, BioBank Qatar, Qatar
2015-presentInternational Scientific Advisory Committee, (ISAC),Qatar
2015-presentVisiting Professor, Juntendo University, Japan
2015-presentExecutive Director, The Japan China Medical Association, Japan
2015-presentDistinguished visiting professor, University at Buffalo, the State University of New York, USA
2016-2018Senior Researcher, Research Institute at SFC, Keio University, Japan
2017-presentCommittee member, The Japan China Medical Association, Japan, Cooperation Committee
2018-presentAuditor-secretary, Association for Rare Variant Surveillance(RVS)
2019-2019Part-time professor, Kyoto University, Japan

AWARDS

1995Tokyo Techno forum Gold Medal Prize, Japan
2000Tsukuba Prize, Japan
2004Commendation by the Minister of Education, Culture, Sports, Science and Technology Japan
2005NISTEP AWARD 2005, Japan
2007Medal with Purple Ribbon, Japan
2010Kihara Prize, The Genomics Society Japan
2010Mochida Commemoration Science Prize, Japan
2012Honorary Doctor of Medicine (MDhc), Karolinska Institute (Sweden)
2013Chen Award for Distinguished Academic Achievement in Human Genetic and Genomic
Research(Human Genome Organization: HUGO)
2016The Australian Museum, 2016 Eureka Prize for Excellence in International Scientific Collaboration (Australia)
2017Symbol of Trust, EIDOS-MEDICINE (Russia)
2017The 58th Science and Technology Firm Festival, Excellence Award, Scientific Frontier, Unlocking the Mysteries of Life with RNA
2019EMBO Associate Member

QUALIFICATIONS

Major international experience:
  General organizer of the international FANTOM1-5 consortium
Major scientific achievements:
  Development of a series of cDNA technologies and its application to establish a mouse genome encyclopedia.
Development of Cap Analysis of Gene Expression (CAGE), gene expression profiling method.
Leading scientist in omics science

SELECTED PEER-REVIWED PUBLICATIONS (Selected from 575 publications)

  1. Kawai J, et al. Functional annotation of a full-length mouse cDNA collection. Nature, 409, 685-690 (2001)
  2. Okazaki Y, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature, 420, 563-73 (2002)
  3. Carninci P, et al. The transcriptional landscape of the mammalian genome. Science, 309, 1559-1563 (2005)
  4. Katayama S, et al. Antisense transcription in the mammalian transcriptome. Science, 309, 1564-1566 (2005)
  5. Carninci P. et al. Genome-wide analysis of mammalian promoter architecture and evolution. Nature Genetics, 38, 626-635 (2006)
  6. Suzuki H, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics, 41, 553-62 (2009)
  7. Y. Maida, et al. An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Nature, 461, 230-235 (2009).
  8. Ravasi T, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell, 140, 744-752 (2010)
  9. Forrest AR, et al. A promoter-level mammalian expression atlas. Nature, 507, 462-470 (2014)
  10. Andersson R, et al. An atlas of active enhancers across human cell types and tissues. Nature 507, 455-461 (2014)
  11. Arner E. et al. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells, Science, 347, 1010-1014 (2015)
  12. Rackham, O.J. et al. A predictive computational framework for direct reprogramming between human cell types. Nat Genet, 48, 331-335(2016).
  13. Chung-Chau Hon, et al. An atlas of human long non-coding RNAs with accurate 5’ ends. Nature, 543, 199-204(2017)
  14. Derek de Rie, et al. The FANTOM5 integrated expression atlas of miRNAs and their promoters.
    Nature Biotechnology (2017)
  15. Hirabayashi, et al. NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements. Nat Genet, 51, 1369-1379(2019)

See also http://fantom.gsc.riken.jp/papers/